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+65 6801 4000 +65 9780 2079
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Cutis Laser Clinics Singapore
Contact us:
9 Scotts Road Pacific Plaza, Scotts Medical Center #08-07, Singapore – 228210
+65 6801 4000
cutis@cutislaserclinics.com

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9 Scotts Road Pacific Plaza, Scotts Medical Center #08-07, Singapore – 228210+65 6801 4000

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Tranexamic Acid: Less Pigment, More Confidence

TXA offers an effective approach to managing hyperpigmentation, particularly melasma. Whether applied topically or taken orally, TXA works to visibly lighten dark spots and inhibit melanin production. It can improve overall skin tone, without the harsh effects associated with bleaching agents.

Tranexamic Acid
PhytoflORAL®
Tranexamic Acid and PhytoflORAL®

How does Tranexamic Acid work?

Originally developed to treat excessive menstrual bleeding, TXA has since been used in dermatology for its pigment-reducing properties. Clinical studies have shown its efficacy in treating melasma and other types of hyperpigmentation. It offers an alternative for patients who may not respond well to traditional treatments.

It helps:

  • Inhibit UV-induced melanocyte activation
  • Reduce vascular factors that contribute to pigmentation
  • Calm skin inflammation, which can worsen discoloration

When taken orally, it works from within to gradually reduce melanin production systemically. When used topically, it provides a more localized effect on targeted areas.

treat excessive menstrual bleeding

How does Tranexamic Acid work?

Pigmentation Treatment

Tranexamic acid targets the root cause of pigmentation by interfering with the melanogenesis process, the formation of melanin in the skin.

Mechanism at a Glance

  • Blocks Plasmin Activity – TXA blocks plasmin, an enzyme that promotes inflammation and melanin-stimulating signals.
  • Disrupts Cell Communication – It prevents keratinocytes from sending signals that overstimulate melanocytes (melanin-producing cells).
  • Reduces Melanin-Stimulating Factors – Lowers levels of prostaglandins and other factors that encourage melanin production.
  • Reduces Melanin Production – With less melanin produced, it can fade existing pigmentation and prevent new spots.

Benefits of Tranexamic Acid

  • Clinically proven to reduce melasma and other pigmentation issues
  • Effective in both oral and topical forms
  • Non-bleaching, non-irritating alternative to hydroquinone
  • Anti-inflammatory and antioxidant properties
  • Improves overall skin brightness and evenness
reduce melasma and other pigmentation

Safety and Efficacy

Oral tranexamic acid for melasma
  • Oral tranexamic acid for melasma – A clinical study reported that the oral use of TXA is a safe and effective therapy for the treatment of melasma. The overall significant improvement was seen in 94.6% of patients (71/74) when they were prescribed with 250 mg of oral tranexamic acid twice daily for 6 months.
  • Topical Use in Dermatology – Topical TXA is a safe and effective treatment for melasma and other types of hyperpigmentation. It also supports skin barrier function, making it ideal for rosacea and post-inflammatory redness. And when combined with microneedling, it enhances results in treating discoloration and post-procedure pigmentation.

FAQs

Is tranexamic acid safe?

Yes, when taken at the right dosage and under medical supervision. However, individuals with a history of blood clotting disorders or stroke should avoid it unless approved by a healthcare provider.

How long before I see results?

Results typically appear within 8–12 weeks of consistent use. Full effects show after 3 to 6 months, especially for oral formulations.

Can I use both oral and topical tranexamic acid together?

Yes, combining both forms may enhance results, particularly for conditions like melasma. However, this should only be done under the guidance of a qualified medical professional.

Are there side effects?

Side effects are rare but may include mild gastrointestinal discomfort or allergic skin reactions. Always consult a doctor if any unusual symptoms arise.

Should I still wear sunscreen?

Absolutely. Tranexamic acid is not a substitute for sunscreen. Daily use of a broad-spectrum SPF 30 or higher is important in maintaining results and preventing new pigmentation.

Who should avoid tranexamic acid?

Those who are pregnant, breastfeeding, or have a history of thromboembolic conditions should not take oral tranexamic acid without medical clearance.

Professional Treatment at Cutis Medical Laser Clinics

At Cutis Medical Laser Clinics, we offer prescription oral and topical tranexamic acid as part of a customized pigmentation treatment plan. Our approach is tailored to your skin type, pigmentation severity, lifestyle, and treatment goals.

Our aesthetic doctors will evaluate your condition and recommend the most effective regimen to help you safely achieve a clearer, more radiant complexion.

Ready to start your journey to brighter, more even skin?

If you're struggling with melasma or stubborn pigmentation, TXA may be the solution you're looking for. Contact us today to book a personalized consultation and discover if oral or topical tranexamic acid is right for your skin.

Need more Information? Have our friendly team contact you to answer any questions.


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